New research will improve treatment of cancer and heart attacks
TSU staff, with colleagues from Tomsk National Research Medical Center (TNIMC), are studying the role of chronic inflammation in the formation and development of cancer and heart attacks. The new research will help to develop a personalized approach to prescribing treatment that will increase the survival rate of cancer and heart attack patients.
- The main object of the study is macrophages, which are cells of innate immunity and play an important role in the adequate response of the body to any invasion, like their predecessors, monocytes, - says Irina Larionova, the project executor, a junior researcher at the TSU Laboratory for Translational Cell and Molecular Biomedicine, junior researcher at the Oncology Research Institute of Tomsk Scientific Research Center. - In cancer, tumor-associated macrophages work on the tumor, contributing to its development and metastasis. It turned out that macrophages are able to program (change their properties) under the influence of antitumor treatment (chemotherapy and radiotherapy) and contribute to the effectiveness of therapy. The specific programming mechanism is still unknown. Part of the project’s research focuses on how monocytes and macrophages can change their functional status in response to chemotherapy.
Read more: http://en.tsu.ru/news/new-research-for-improved-treatment-of-cancer-and-heart-attacks-is-und/
