Scientists created the world's first Compton microscope
TSU radiophysicists and scientists from German Electron Synchrotron (DESY) national research center have completed developing and testing the world's first Compton microscope, which makes it possible to research at the subcellular level, that is, to study living, functioning cells without preparation. This device of a new class based on scattered radiation does not destroy the object of study after it is irradiated with an X-ray beam, in contrast to transmission X-ray microscopy.
The main task was to reduce the X-ray dose when reconstructing a three-dimensional image of biological samples with high spatial resolution. The joint development of TSU and colleagues from DESY significantly increases the exposure time in the study of cell structures, tissues, and long protein molecules, which are rapidly destroyed in a transmission X-ray microscope due to the large absorbed dose. In the new device, the impact is weaker, which means that the destruction will be slower.