Laboratory of Superfine Material Biosafety
Room 10, 36, Lenin Ave., Tomsk, 634050, Russia;
Phone: +7 3822 534-519
Areas of Research
Main spheres of research
Development of methodology and methods of determination and quantitative assessment of biological danger of nanomaterials and nanoparticles.
Research on the possibility and danger of translocation of nanoparticles in the organism via food chains.
The aim of the project is to develop the system of analysis and quantitative evaluation of bioaccumulation, translocation and toxicity of superfine materials (SFM) and waste products containing nanoparticles and highly dispersed components in the food chains, taking into account the dynamic of the stability of highly disperse systems.
Objectives:
Basic research on the development of a methodology for assessing the environmental safety of aqueous dispersions of SFM, taking into account the dynamics of their aggregate stability, and applied research in developing methods for:
1) The standard physical and chemical characterization of SFM aqueous dispersions and evaluation of the effective concentration of free nanoparticles in test system.
2) Preliminary analysis of toxicity of SFMs under research during their life cycle to determine the necessary protection measures in research works.
3) Determination of toxicity (including phytotoxicity) of soil contaminated with SFM.
4) Development of a methodology for determining the nanoparticles in aqueous media via voltammetric method.
In subsequent years, the following tasks will be solved:
1) Determination of toxicity (including phytotoxicity) of surface water, groundwater and wastewater contaminated with nanoparticles.
2) Determination of toxic effects of SFMs on unicellular and multicellular organisms of different trophic levels.
3) Development of a technology of research a bioaccumulation of SFMs.
4) Development of a technology of research a translocation of nanoparticles in the food chains.
5) Development of methods for determining the toxicity of nanomaterials using tissue culture.
Partners
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A.N. Bach Institute of Biochemistry RAS (Moscow)
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Institute of Nutrition RAMS (Moscow)
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Laboratory of ecotoxicological analysis of soils MSU (Moscow)
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Moscow Institute of Steel and Alloys
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Siberian Federal University (Krasnoyarsk)
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MicroBioTests Inc., Ghent University (Belgium).
Centre of Excellence
Centre for High Technologies in MedicineQS subject
- Agriculture & Forestry
- Biological Sciences
- Medicine
